vitamin d 3 การใช้

• Cholecalciferol naturally occurs as vitamin D 3 in many foods, including fish.
• One of the most common such electrocyclizations is the biosynthesis of vitamin D 3.
• A [ 1, 7 ]-hydride shift then forms vitamin D 3.
• In the liver, cholecalciferol ( vitamin D 3 ) is converted to calcifediol.
• It takes about ten days for the body to process vitamin D 3 into calcitriol.
• FACL3 contributes to vitamin D 3 growth inhibitory effect in human prostate cancer LNCaP cells.
• Calcitriol ( 1, 25-dihydroxycholecalciferol ) is the active form of vitamin D 3.
• Calcitriol, the active metabolite of vitamin D 3, appears to be a catalyst for glutathione production.
• In 1949 Alfred Schubert, who first developed a method of synthesis of vitamin D 3 10 years later ).
• Vitamin D 3 is produced photochemically from 7-dehydrocholesterol in the skin of most vertebrate animals, including humans.
• In regulating the level of vitamin D 3, this enzyme plays a role in calcium homeostasis and the vitamin D endocrine system.
• Vitamin D 3, however, appears to decrease the risk of death from cancer but concerns with the quality of the data exist.
• In 1935, the chemical structure of vitamin D 3 was established and proven to result from the ultraviolet irradiation of 7-dehydrocholesterol.
• Calcifediol is then hydroxylated in the kidney, and becomes calcitriol ( 1, 25-dihydroxyvitamin D 3 ) or active vitamin D 3.
• The ultraviolet radiation in sunlight has both positive and negative health effects, as it is both a principal source of vitamin D 3 and a mutagen.
• Endogenously synthesized vitamin D 3 travels mainly with vitamin D-binding protein, which slows hepatic delivery of vitamin D and the availability in the plasma.
• Under the influence of ultraviolet light on the skin, cholesterol is converted to previtamin D 3 which spontaneously isomerizes to vitamin D 3 ( or cholecaliferol ).
• "' Ideos "'is a dietary supplement, consisting of calcium in the form of calcium carbonate, as well as vitamin D 3.
• The low levels of PTH also inhibit the formation of calcitriol ( 1, 25 dihydroxyvitamin D 3 ) from cholecalciferol ( vitamin D 3 ) by the kidneys.
• Biochemically in blood, XLH is recognized by hypophosphatemia and an inappropriately low level of calcitriol ( 1, 25-( OH ) 2 vitamin D 3 ).